Publications & Success Stories

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human body outlines made of bacterial shapes

The TransUniversity Microbiome Initiative is excited to announce the third round of Awardees for the Fall 2021 (Round 3) TUMI Pilot and Feasibility Grants. TUMI assembled a panel of over twenty reviewers to assess and select our 8 finalists. Below you will find brief summaries of each of the eight funded projects. TUMI looks forward to supporting this research over the coming months, and we are unbelievably excited by the creative microbiome research proposed across grounds. Stay tuned for microbiome research updates from each of these investigators!!

 

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Ocean water with bubbles viewed from under the surface

Did you know 1/4 of carbon derived from photosynthesis on Earth cycles through the ocean’s microbe network in minutes to days? We just learned this from the new National Science Foundation Science Technology Center! The Center for Chemical Currencies of a Microbial Planet (c-COMP) will explore how this works with chemistry, biology, modeling, informatics and education research!

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coffee cup and a laptop

The TransUniversity Microbiome Initiative is excited to announce the second round of Awardees for the Spring 2021 (Round 2) TUMI Pilot and Feasibility Grants. Nine investigators submitted applications and TUMI assembled a panel of over twenty reviewers to assess and select our finalists. Below you will find brief summaries of each of the six funded projects. TUMI looks forward to supporting this research over the coming months, and we are unbelievably excited by the creative microbiome research proposed across grounds. Selecting only a handful to fund was not an easy task.

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bacteria in the gut

Microbiome Publications from UVA

(October 2019 - September 2020)

 

  1. Gut microbiome communication with bone marrow regulates susceptibility to amebiasis. Journal of Clinical Investigation. May 2020. Stacey L. Burgess, Jhansi L. Leslie, Md. Jashim Uddin, David Noah Oakland, Carol A. Gilchrist, G. Brett Moreau, Koji Watanabe, Mahmoud M. Saleh, Morgan Simpson, Brandon A. Thompson, David T. Auble, Stephen D. Turner, Natasa Giallourou, Jonathan Swann, Zhen Pu, Jennie Z. Ma, Rashidul Haque, and William A. Petri, Jr.

 

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UVA TUMI

The TransUniversity Microbiome Initiative is thrilled to announce the Awardees of our first round of TUMI Pilot and Feasibility Grants. Nineteen investigators submitted applications and TUMI assembled a panel of over twenty reviewers to assess and select our finalists. Below you will find brief summaries of each of the funded projects. TUMI looks forward to supporting this research over the coming months, and we are unbelievably excited by the creative microbiome research proposed across grounds. Selecting only a handful to fund was not an easy task.

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C. difficile bacteria

Earlier this month, we received news that our co-director, William Petri Ph.D. (ID&IH), and a team of researchers here at UVA have been awarded an NIH R01 (R01 AI152477-01A1) grant. The team will study the mechanisms by which specific parts of our immune system control the our response to C. difficile infection. 

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Image of the lawn with sun coming through trees

The TransUniversity Microbiome Initiative is hiring for multiple data science/bioinformatician positions. The first two are posted through the Department of Pediatrics, see links below! Additional positions will be posted through the Department of Medicine, Division of Infectious Disease and International Health.

 

Please reach out to Casandra Hoffman (clh4he@virginia.edu) with any additional questions. 

 

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(A) Principal Coordinate Analysis (PCoA) of Bray- 216 Curtis dissimilarities (beta-diversity) of fecal microbiota from surveillance reference stool or E. 217 histolytica infected children. The groups are significantly different by PERMANOVA. (B) 218 Relative abundance of the genus Lachnoclostridium from samples described in A. The groups 219 are significantly different by Wilcoxon rank sum test with continuity correction.

Stacey Burgess, Assistant Professor of Medicine, Infectious Diseases and International Health was just awarded an R01 to study mechanisms by which microbiota protect against infection (R01 R01AI146257: “Gut microbiome communication with the bone marrow regulates intestinal inflammation”). Using data generated in TUMI’s Gnotobiotic Germ-Free Animal Core, she put together a competitive application and was notified of her success in mid-January! Feel free to reach out to her if you have questions about her experience with the Gnotobiotic Facility!

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SOM Research Retreat 2020

The School of Medicine Research Retreat was an amazing opportunity to learn about the research going on at the University of Virginia and to build research connections with SOM faculty.